Ramucirumab (Cyramza) is a FDA-approved treatment for non-small cell lung cancer (NSCLC) that has metastasized.
It is used:
- With erlotinib hydrochloride as first-line therapy in patients whose disease has certain mutations in the EGFR gene.
- With docetaxel in patients whose disease has gotten worse during or after treatment with platinum chemotherapy.
- For patients whose disease has a mutation in the EGFR gene or ALK gene, ramucirumab is used if their disease has gotten worse after treatment with FDA-approved therapy for these mutations.